EB2 pS222 antibody

EB2 S222 site is a target for phosphorylation by the CDKL5 protein kinase; loss-of-function mutations in the human CDKL5 gene are associated with CDKL5 Deficiency Disorder, a neurodevelopmental disorder with intractable epilepsy (Baltussen, Negraes, et al

PDF) Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125

Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

Litterature

Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability

EB2 pS222 antibody

Rockland畅销品，2022年价格表（三） - 每日生物评论

Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125, Microbial Cell Factories

JCI - Temporal manipulation of Cdkl5 reveals essential postdevelopmental functions and reversible CDKL5 deficiency disorder–related deficits

Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability